<p>Binding levels of EAPB0203, EAPB0503 and imiquimod were determined by surface plasmon resonance on immobilized tubulin at different concentrations (n = 4, except for colchicine n = 1).</p
<p>DNA immobilization as described in Fig. 2. CcmR binding to pndhF3 fragments as the binding target...
We recently developed a binding assay format by incorporating native transmembrane receptors into ar...
A unique property of tubulin is to bind colchicine and colcemid, two structurally similar drugs, bot...
International audienceDisplaying a strong antiproliferative activity on a wide variety of cancer cel...
Displaying a strong antiproliferative activity on a wide variety of cancer cells, EAPB0203 and EAPB0...
<p>Purified tubulin polymerization was quantitated by turbidimetry measurement at 350 nm with or wit...
<p>A375 cells were treated by EAPB0203, EAPB0503 and imiquimod at the indicated concentrations for 2...
<p>(A) Size exclusion chromatograms for p150 Nt-GCN4 run alone or pre-incubated with tubulin reveal ...
<p>(<i>A</i>) Interaction with <sup>125</sup>I-CB3 was measured in a pull-down assay with, <i>M3-GST...
<p>(A) MPT0B214 inhibits microtubule assembly in vitro. MAP-rich tubulin was incubated at 37°C in th...
<p>Green = hydrophobic residues; red = polar residues; white = non-interacting residues. Using Molec...
<p>(A) <i>In-vitro</i> tubulin polymerization assays were used to test the effect of the 212 mitotic...
Abstract Development of antimitotic binding to the colchicine-binding site for the treatment of canc...
AbstractBinding of two colchicine analogues, desacetamidocolchicine and 2-methoxy-5-(2′,3′,4′-trimet...
<p>A comparison of the binding abilities between recombinant GST-Sli15-His<sub>6</sub> and its mutan...
<p>DNA immobilization as described in Fig. 2. CcmR binding to pndhF3 fragments as the binding target...
We recently developed a binding assay format by incorporating native transmembrane receptors into ar...
A unique property of tubulin is to bind colchicine and colcemid, two structurally similar drugs, bot...
International audienceDisplaying a strong antiproliferative activity on a wide variety of cancer cel...
Displaying a strong antiproliferative activity on a wide variety of cancer cells, EAPB0203 and EAPB0...
<p>Purified tubulin polymerization was quantitated by turbidimetry measurement at 350 nm with or wit...
<p>A375 cells were treated by EAPB0203, EAPB0503 and imiquimod at the indicated concentrations for 2...
<p>(A) Size exclusion chromatograms for p150 Nt-GCN4 run alone or pre-incubated with tubulin reveal ...
<p>(<i>A</i>) Interaction with <sup>125</sup>I-CB3 was measured in a pull-down assay with, <i>M3-GST...
<p>(A) MPT0B214 inhibits microtubule assembly in vitro. MAP-rich tubulin was incubated at 37°C in th...
<p>Green = hydrophobic residues; red = polar residues; white = non-interacting residues. Using Molec...
<p>(A) <i>In-vitro</i> tubulin polymerization assays were used to test the effect of the 212 mitotic...
Abstract Development of antimitotic binding to the colchicine-binding site for the treatment of canc...
AbstractBinding of two colchicine analogues, desacetamidocolchicine and 2-methoxy-5-(2′,3′,4′-trimet...
<p>A comparison of the binding abilities between recombinant GST-Sli15-His<sub>6</sub> and its mutan...
<p>DNA immobilization as described in Fig. 2. CcmR binding to pndhF3 fragments as the binding target...
We recently developed a binding assay format by incorporating native transmembrane receptors into ar...
A unique property of tubulin is to bind colchicine and colcemid, two structurally similar drugs, bot...