<p>A375 cells were treated by EAPB0203, EAPB0503 and imiquimod at the indicated concentrations for 24h. Beta-tubulin was stained using a mouse monoclonal anti-β-tubulin antibody and a secondary Rhodamine-labeled anti-mouse antibody. Nuclei were stained with Hoechst. Microtubule network (green) and nuclear DNA (red) were visualized using a Leica DMRM fluorescence microscope with a 63x magnification. Representative images are displayed here.</p
International audienceMicrotubules are still a promising target for new therapeutic agents. Thus, th...
Tubulin is a protein that plays a critical role in maintaining cellular structure and facilitating c...
International audienceMicrotubules are still a promising target for new therapeutic agents. Thus, th...
International audienceDisplaying a strong antiproliferative activity on a wide variety of cancer cel...
International audienceDisplaying a strong antiproliferative activity on a wide variety of cancer cel...
The imidazoquinoxalines (imiqualines), original bioactive molecules and chemical analogues of imiqui...
<p>(A) RCC cells were treated with 10 and 30 nM ELR510444 for 24 h. Cell cycle distribution was dete...
<p>In the DAPI panel of the F3.1.1, paclitaxel or cembrene-treated cells, the red arrow indicates a ...
<p><b>A)</b> Hela and <b>B)</b> 3T3 MEFs were fixed and incubated with antibodies against RanBPM and...
<p>Representative images of cells treated with RANKL and LPS/IFNγ from early Day 3 of the differenti...
Background: Drug resistance is a common cause of treatment failure in cancer patients and encompasse...
<p>Synchronized cells were treated with T44Bf (10 μM and 20 μM) or Vincristine (200 nM) for 15h. Cel...
<p>Binding levels of EAPB0203, EAPB0503 and imiquimod were determined by surface plasmon resonance o...
Tubulin is a protein that plays a critical role in maintaining cellular structure and facilitating c...
<p>Cells were seeded onto glass coverslips in 12-well plates, exposed to MIR for 48 hours, fixed for...
International audienceMicrotubules are still a promising target for new therapeutic agents. Thus, th...
Tubulin is a protein that plays a critical role in maintaining cellular structure and facilitating c...
International audienceMicrotubules are still a promising target for new therapeutic agents. Thus, th...
International audienceDisplaying a strong antiproliferative activity on a wide variety of cancer cel...
International audienceDisplaying a strong antiproliferative activity on a wide variety of cancer cel...
The imidazoquinoxalines (imiqualines), original bioactive molecules and chemical analogues of imiqui...
<p>(A) RCC cells were treated with 10 and 30 nM ELR510444 for 24 h. Cell cycle distribution was dete...
<p>In the DAPI panel of the F3.1.1, paclitaxel or cembrene-treated cells, the red arrow indicates a ...
<p><b>A)</b> Hela and <b>B)</b> 3T3 MEFs were fixed and incubated with antibodies against RanBPM and...
<p>Representative images of cells treated with RANKL and LPS/IFNγ from early Day 3 of the differenti...
Background: Drug resistance is a common cause of treatment failure in cancer patients and encompasse...
<p>Synchronized cells were treated with T44Bf (10 μM and 20 μM) or Vincristine (200 nM) for 15h. Cel...
<p>Binding levels of EAPB0203, EAPB0503 and imiquimod were determined by surface plasmon resonance o...
Tubulin is a protein that plays a critical role in maintaining cellular structure and facilitating c...
<p>Cells were seeded onto glass coverslips in 12-well plates, exposed to MIR for 48 hours, fixed for...
International audienceMicrotubules are still a promising target for new therapeutic agents. Thus, th...
Tubulin is a protein that plays a critical role in maintaining cellular structure and facilitating c...
International audienceMicrotubules are still a promising target for new therapeutic agents. Thus, th...