Effects of PA024 on mRNA expression of other enzymes involved in steroid synthesis.

<p>(A)-(G), total RNAs extracted from the cells treated with PA024 (10 μmol/L, 24 h) and Ang II (100 nmol/L, 6 h) were examined for mRNA expression of <i>StAR</i>, <i>CYP11A1</i>, <i>HSD3β1</i>, <i>HSD3β2</i>, <i>CYP21A2</i>, <i>CYP17A1</i> and <i>CYP11B1</i> by quantitative real-time PCR. Data represent mean ± S.E.M. (n = 4), percent of control, normalized by β-actin mRNA levels. ***<i>P</i><0.001 vs. control, ^†<i>P</i><0.05 vs. Ang II.