Supplementary Material for: Epidemiology of Multiple Sclerosis in Austria

<p><b><i>Background:</i></b> To assess the incidence rate and prevalence ratio of multiple sclerosis (MS) in Austria. <b><i>Methods:</i></b> Hospital discharge diagnosis and MS-specific immunomodulatory treatment prescriptions from public health insurances, covering 98% of Austrian citizens with health insurance were used to extrapolate incidence and prevalence numbers based on the capture-recapture method. <b><i>Results:</i></b> A total of 1,392,629 medication prescriptions and 40,956 hospitalizations were extracted from 2 data sources, leading to a total of 13,205 patients. The incidence rate and prevalence ratio of MS in Austria based on the capture-recapture method were 19.5/100,000 person-years (95% CI 14.3-24.7) and 158.9/100,000 (95% CI 141.2-175.9), respectively. Female to male ratio was 1.6 for incidence and 2.2 for prevalence. <b><i>Conclusions:</i></b> Incidence rates and prevalence ratios of MS in our study are within the upper range of comparable studies across many European countries as well as the United States.