PD-1 and CTLA-4 expressions on Singlet/FVS 510-/Lymph/CD3-/CD4-/CD8- B cells.

<p>Representative contour plot of <b>(A)</b> PD-1 and CTLA-4 expressions on B cells of uninfected, OB-infected and OS-infected mice after 60 days of infection. <b>(B)</b> PD-1+ and <b>(C)</b> CTLA-4+ percentage of uninfected, OB-infected and OS-infected mice. Data are pooled from two independent experiments (A-C; n = 6 per group). Scatter dot plots show the median value (line), the interquartile range (whiskers). <i>P</i> values calculated using Mann-Whitney U test. *<i>P</i><0.025, **<i>P</i><0.005, ***<i>P</i><0.0005 after Bonferroni correction for 2 comparisons.