Methods: A detailed description of the analysis methods used for the detection of somatic mutations with an unmatched pool of normal samples. (DOCX 106Â kb
Section S1POLE mutation patterns in colon cancer samples. Section S2 Detailed forward model selectio...
Table S2. Comprehensive list of somatic mutations, gene symbols, Ensemble gene IDs, chromosome numbe...
Figure S2. Mean sequencing read depth for (A.) the 46 solid tumor cohort. (B.) isolated mononuclear ...
Supplementary text. It contains detailed results of our analyses in Figures S1âS7 and Tables S1â...
Detailed information of all somatic mutations in targeted amplicon sequencing (TAS), including cover...
All supplementary tables merged. 1: List of all identified SiMPRes. 2: All novel genes that contain ...
The relationship between nucleotide diversity of the gene sequences and the densities of somatic mut...
Detailed information of all somatic mutations identified by WES, including coverage, variant allele ...
Figure S4. Tumor mutational burden across all samples in the 46 solid tumor cohort. (A.) Total detec...
Figure S1. Determination of the minimum sample size for the experiments (a) 5 percentile of the 100,...
Supplementary results. This file contains supplementary tables and figures. Explanatory text is incl...
List of simple somatic mutations across all six regions of the tumor, including SNVs and small INDEL...
Large tumor dataset quality control metrics. A. Principal component analysis and B. loadings using s...
Total number of deleterious somatic mutations normalized by gene length in 52 CBT samples. (XLSX 132...
Figure S1. MammaSeq⢠gene coverage. The percentage of protein coding bases pairs in each gene that...
Section S1POLE mutation patterns in colon cancer samples. Section S2 Detailed forward model selectio...
Table S2. Comprehensive list of somatic mutations, gene symbols, Ensemble gene IDs, chromosome numbe...
Figure S2. Mean sequencing read depth for (A.) the 46 solid tumor cohort. (B.) isolated mononuclear ...
Supplementary text. It contains detailed results of our analyses in Figures S1âS7 and Tables S1â...
Detailed information of all somatic mutations in targeted amplicon sequencing (TAS), including cover...
All supplementary tables merged. 1: List of all identified SiMPRes. 2: All novel genes that contain ...
The relationship between nucleotide diversity of the gene sequences and the densities of somatic mut...
Detailed information of all somatic mutations identified by WES, including coverage, variant allele ...
Figure S4. Tumor mutational burden across all samples in the 46 solid tumor cohort. (A.) Total detec...
Figure S1. Determination of the minimum sample size for the experiments (a) 5 percentile of the 100,...
Supplementary results. This file contains supplementary tables and figures. Explanatory text is incl...
List of simple somatic mutations across all six regions of the tumor, including SNVs and small INDEL...
Large tumor dataset quality control metrics. A. Principal component analysis and B. loadings using s...
Total number of deleterious somatic mutations normalized by gene length in 52 CBT samples. (XLSX 132...
Figure S1. MammaSeq⢠gene coverage. The percentage of protein coding bases pairs in each gene that...
Section S1POLE mutation patterns in colon cancer samples. Section S2 Detailed forward model selectio...
Table S2. Comprehensive list of somatic mutations, gene symbols, Ensemble gene IDs, chromosome numbe...
Figure S2. Mean sequencing read depth for (A.) the 46 solid tumor cohort. (B.) isolated mononuclear ...
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