<p>Survival of HeLa cells in the presence of 1X and 5X MIC concentrations of inhibitors. INH was taken as a positive control. The experiments were done in duplicate and the data was represented as mean ± SD.</p
<p>MCF7 sensitive cells (6×10<sup>4</sup>) were plated in 1 ml medium and treated with 1 µM GSH (lig...
<p>Cytotoxic activity against HeLa cell line, calculated for all samples tested.</p
<p>Survival percentages of SHSY5Y cells incubated with 30 µM Aβs for 72 hours. Wells containing SHSY...
<p>Cells were incubated with the indicated concentrations of compounds for 18λ = 570 nm after the ad...
<p>Cells were treated with various compounds for 4h, and grown for another 20h. (A)IC50 of HeLa and ...
<p>(A) Cytotoxic activity of compounds <b>1</b>, <b>2</b>, and <b>5</b> against cancer cells. The in...
<p>Percent cell survival in the control group was assumed 100%. (A) ZINC01807204 (B) ZIC02318494. n ...
<p>A, Cytotoxic effects of DOX alone and DOX+LMB on cell viability of A549 cells as determined by th...
<p>Relative to the untreated control, which was normalized to 0% in both assays, reduction in cell v...
Cytotoxicity of the selected MtTopoI inhibitor compounds in human cell lines.</p
(A-D) LLC-PK cells grown in 96-well plates in triplicate were treated with various concentrations of...
<p><sup><i>a</i></sup> The IC<sub><b>50</b></sub> values were determined by the MTT assay after 48 h...
<p>AGS or AGS-BX1 cells were incubated with various concentrations of the hit compounds for 48h and ...
<p>Columns filled with black, gray and white represent OAR19, OAR22 and OAR27, respectively. The cel...
<p>SW-480, SW-620, Caco-2 and HEK-293 cells viability after FPKc (A, B, C, D) and ES (E) treatment w...
<p>MCF7 sensitive cells (6×10<sup>4</sup>) were plated in 1 ml medium and treated with 1 µM GSH (lig...
<p>Cytotoxic activity against HeLa cell line, calculated for all samples tested.</p
<p>Survival percentages of SHSY5Y cells incubated with 30 µM Aβs for 72 hours. Wells containing SHSY...
<p>Cells were incubated with the indicated concentrations of compounds for 18λ = 570 nm after the ad...
<p>Cells were treated with various compounds for 4h, and grown for another 20h. (A)IC50 of HeLa and ...
<p>(A) Cytotoxic activity of compounds <b>1</b>, <b>2</b>, and <b>5</b> against cancer cells. The in...
<p>Percent cell survival in the control group was assumed 100%. (A) ZINC01807204 (B) ZIC02318494. n ...
<p>A, Cytotoxic effects of DOX alone and DOX+LMB on cell viability of A549 cells as determined by th...
<p>Relative to the untreated control, which was normalized to 0% in both assays, reduction in cell v...
Cytotoxicity of the selected MtTopoI inhibitor compounds in human cell lines.</p
(A-D) LLC-PK cells grown in 96-well plates in triplicate were treated with various concentrations of...
<p><sup><i>a</i></sup> The IC<sub><b>50</b></sub> values were determined by the MTT assay after 48 h...
<p>AGS or AGS-BX1 cells were incubated with various concentrations of the hit compounds for 48h and ...
<p>Columns filled with black, gray and white represent OAR19, OAR22 and OAR27, respectively. The cel...
<p>SW-480, SW-620, Caco-2 and HEK-293 cells viability after FPKc (A, B, C, D) and ES (E) treatment w...
<p>MCF7 sensitive cells (6×10<sup>4</sup>) were plated in 1 ml medium and treated with 1 µM GSH (lig...
<p>Cytotoxic activity against HeLa cell line, calculated for all samples tested.</p
<p>Survival percentages of SHSY5Y cells incubated with 30 µM Aβs for 72 hours. Wells containing SHSY...