Chemosensitivity screening is possible using spheroid cultures.
- Maria Jeppesen (4416340)
- Grith Hagel (2147842)
- Anders Glenthoj (4416337)
- Ben Vainer (344474)
- Per Ibsen (4416331)
- Henrik Harling (4416328)
- Ole Thastrup (4416334)
- Lars N. Jørgensen (4416343)
- Jacob Thastrup (2147839)
Publication date
September 2017
DOIAbstract
<p>(A) Screening results for spheroid cultures exposed to common chemotherapy drugs and combinations from five patients. ED25: the dose at which a given drug resulted in 25% growth reduction compared to untreated spheroids. * poor curve fit, however, max growth reduction was 17% so ED25 was assigned >500nM. (B) Curve fit graphs for Pt.20 and Pt.21 demonstrating different chemosensitivity profiles.</p
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