Effect of DMSO, HIV-1ADA gp120, PPARγ agonists on cell viability in vitro. Primary cultures of mixed rat astrocytes and microglia were treated with either DMSO, gp120 (5 nM), rosiglitazone (1 μM), pioglitazone (20 μM, 50 μM) or GW9662 (500 nM) for 6 h, and cell viability was assessed using MTT assay. Results are expressed as percent of control and reported as mean ± SEM of at least 3 separate experiments (PDF 25 kb
HIV-1-infected macrophages induce neurotoxicity through GLS1-containing MVs. (A-F) At 7Â days post-i...
Subcellular localization of HIV-1 IN, MA, and Vpr in transfected cells. Figure S1. Subcellular distr...
Figure S1. Survival of primary microglia in the presence of inflammatory mediators. * p < 0.05, ** p...
PPARγ agonists rosiglitazone and pioglitazone reverse HIV-1ADA gp120-mediated inflammatory responses...
PPARγ agonist rosiglitazone reverses HIV-1ADA gp120-mediated inflammatory responses in frontal corte...
Effect of HIV-1ADA gp120 on the mRNA and protein expression of PPARγ in frontal cortex. Adult Wistar...
LRA are well-tolerated by astrocytes. The metabolic activity of astrocytes was assessed using a MTS ...
Representative image (on top) showing the characteristic ratio of astrocytes-to-microglia in the cor...
Primary mouse astrocyte cultures differentially express GLAST and GLT-1 transporters. (A) Cortical a...
Despite the use of combinational antiretroviral therapy (cART) for the treatment of HIV-1 infection,...
Co-culture secretion of cytokines is elevated compared to mono-culture secretion. The co-culture of ...
EcoHIV infection induces the expression of pro-inflammatory genes in primary microglia. Real-time PC...
Figure S1. Distribution of GFP in CNS of mice infected by lentivirus. The lentivirus suspension of L...
Figure S1. Quantitative real-time PCR (RT-qPCR) data showing the expressions of iNOS, COX-2, cytokin...
Expression of GPR55 mRNA in primary rat microglia with or without LPS stimulation. Microglia were in...
HIV-1-infected macrophages induce neurotoxicity through GLS1-containing MVs. (A-F) At 7Â days post-i...
Subcellular localization of HIV-1 IN, MA, and Vpr in transfected cells. Figure S1. Subcellular distr...
Figure S1. Survival of primary microglia in the presence of inflammatory mediators. * p < 0.05, ** p...
PPARγ agonists rosiglitazone and pioglitazone reverse HIV-1ADA gp120-mediated inflammatory responses...
PPARγ agonist rosiglitazone reverses HIV-1ADA gp120-mediated inflammatory responses in frontal corte...
Effect of HIV-1ADA gp120 on the mRNA and protein expression of PPARγ in frontal cortex. Adult Wistar...
LRA are well-tolerated by astrocytes. The metabolic activity of astrocytes was assessed using a MTS ...
Representative image (on top) showing the characteristic ratio of astrocytes-to-microglia in the cor...
Primary mouse astrocyte cultures differentially express GLAST and GLT-1 transporters. (A) Cortical a...
Despite the use of combinational antiretroviral therapy (cART) for the treatment of HIV-1 infection,...
Co-culture secretion of cytokines is elevated compared to mono-culture secretion. The co-culture of ...
EcoHIV infection induces the expression of pro-inflammatory genes in primary microglia. Real-time PC...
Figure S1. Distribution of GFP in CNS of mice infected by lentivirus. The lentivirus suspension of L...
Figure S1. Quantitative real-time PCR (RT-qPCR) data showing the expressions of iNOS, COX-2, cytokin...
Expression of GPR55 mRNA in primary rat microglia with or without LPS stimulation. Microglia were in...
HIV-1-infected macrophages induce neurotoxicity through GLS1-containing MVs. (A-F) At 7Â days post-i...
Subcellular localization of HIV-1 IN, MA, and Vpr in transfected cells. Figure S1. Subcellular distr...
Figure S1. Survival of primary microglia in the presence of inflammatory mediators. * p < 0.05, ** p...