Liver abnormalities detected in HCV infected mice at 27 weeks post infection.

<p>(A-H) Livers were harvested from mice in the mock and HCV infected groups, paraffin-embedded and processed for staining with (B-G) haematoxylin and eosin or (H) Sirius red/fast green stains. (A) Representative image showing gross appearance of livers obtained from either mock or HCV infected mice at 27–28 weeks post infection. Representative image of H&E stains showing (B) normal liver from mock infected mice and (C) steatosis, (D) hepatocellular adenoma, (E) hepatocellular carcinoma, (F) granulomatous inflammation, (G) focal nodular hyperplasia and (H) liver fibrosis from livers harvested from HCV infected mice.