Data synthesis to generate maps of protein dynamics during cell-cycle progression and cell-cycle exit.

<p>(A) Moving average traces from <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2003268#pbio.2003268.g003" target="_blank">Fig 3</a> Column 2 were normalized such that the minimum signal experienced across CDK2^inc and CDK2^low data for a given protein was set to 0, and the maximum signal experienced across CDK2^inc and CDK2^low data for this protein was set to 1. The approximate time spent in G1, S, or G2 phases is marked above the plots, based on EdU incorporation data from <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2003268#pbio.2003268.g001" target="_blank">Fig 1H</a>. Group 1 (top row): protein signals that are “off” in quiescent cells. Group 2 (bottom row): protein signals that change dynamically over time in quiescent cells. (B) Schematized representation of the data from (A).