This file contains data on mutant allele frequencies and homozygote mutant genotype frequencies at various time points (generations) in independent, replicate populations experimentally evolving in either a complex or simple mating environment. Each row corresponds to a frequency estimate from a particular population in a given generation. Columns are: mutant: the mutation in question; population: an arbitrary ID number given to each replicate population (6 populations per mutation, 3 in each treatment); treatment: simple vs. complex mating treatment; generation: the generation in which the given frequency was estimated; type: whether the frequency is that of the mutant allele (as estimate from a set of test crosses) or the mutant homozygot...
<p><i>P<sub>aa</sub></i> and <i>P<sub>Aa</sub></i> are frequencies of recessive (mutated) homozygote...
<p>Columns 1–2: possible genotypes, two columns represent first and second chromatid. Third column: ...
Mutant (disorder-causing) allele frequency, f(m), for each disorder/breed per year of birth relative...
This file contains data on mutant allele frequencies and homozygote mutant genotype frequencies at v...
This file contains data from test crosses conducted to determine wildtype and mutant (gene disruptio...
<p>Panels in the upper row show averaged allele frequency dynamics over 25 generations after an alle...
Summarized simulation result files for deleterious mutations. Row 1 of each file contains column hea...
Mutant (disorder-causing) allele frequency, f(m), for each disorder/breed per year of birth relative...
Summarized simulation result files for deleterious mutations. Row 1 of each file contains column hea...
This file contains the following information / 1st column: alleles at each locus / 2nd to 6th column...
This file contains the following information / 1st column: alleles at each locus / 2nd to 6th column...
<p>Dark grey are populations evolved in the benign environment and light grey are the populations ev...
This data set describes the frequencies of mutant alleles relative to the ancestral genome in Sindbi...
<p>(A) Shown are the expected and observed mean sample frequencies of disease mutations for four dif...
(A-C) Observed frequency of region-wide haplotypes (RWH) during experimental evolution, for region 1...
<p><i>P<sub>aa</sub></i> and <i>P<sub>Aa</sub></i> are frequencies of recessive (mutated) homozygote...
<p>Columns 1–2: possible genotypes, two columns represent first and second chromatid. Third column: ...
Mutant (disorder-causing) allele frequency, f(m), for each disorder/breed per year of birth relative...
This file contains data on mutant allele frequencies and homozygote mutant genotype frequencies at v...
This file contains data from test crosses conducted to determine wildtype and mutant (gene disruptio...
<p>Panels in the upper row show averaged allele frequency dynamics over 25 generations after an alle...
Summarized simulation result files for deleterious mutations. Row 1 of each file contains column hea...
Mutant (disorder-causing) allele frequency, f(m), for each disorder/breed per year of birth relative...
Summarized simulation result files for deleterious mutations. Row 1 of each file contains column hea...
This file contains the following information / 1st column: alleles at each locus / 2nd to 6th column...
This file contains the following information / 1st column: alleles at each locus / 2nd to 6th column...
<p>Dark grey are populations evolved in the benign environment and light grey are the populations ev...
This data set describes the frequencies of mutant alleles relative to the ancestral genome in Sindbi...
<p>(A) Shown are the expected and observed mean sample frequencies of disease mutations for four dif...
(A-C) Observed frequency of region-wide haplotypes (RWH) during experimental evolution, for region 1...
<p><i>P<sub>aa</sub></i> and <i>P<sub>Aa</sub></i> are frequencies of recessive (mutated) homozygote...
<p>Columns 1–2: possible genotypes, two columns represent first and second chromatid. Third column: ...
Mutant (disorder-causing) allele frequency, f(m), for each disorder/breed per year of birth relative...