<p>Across samples from (A) all 103 patients, (B) ETS-positive cancers, and (C) ETS-negative cancers. SCNAs present in more than one patient were plotted. The green lines represent the cut-off (5 patients) for defining recurrently altered regions. Chromosome numbers are indicated in black. Genes potentially involved in prostate cancer development in the minimal regions of alteration are annotated in black.</p
<p>Boxplots show the CNA frequency distributions among tumor samples in 10 randomly selected cancer ...
Prostate cancer cell lines provide ideal in vitro systems for the identification and analysis of pro...
SummaryLittle is understood about the occurrence of somatic genomic alterations in normal tissues an...
<p>(A) Histogram of frequency of amplification (red) or deletion (blue) of genome sequences of leuko...
Determining how somatic copy-number alterations (SCNAs) promote cancer is an important goal. We char...
a) Barplot showing the number of samples per tumour and colored by WGD clonality status with clonal ...
a) Barplots showing the proportion of the genome affected by MSAI in each tumour sample in the pan-c...
<p>Cases are grouped by mutation and SCNA status. Top panel: only significant clustering genes are s...
<p>Panel A shows box plots with the distribution of tumors (n = 31) according to the percentage of t...
<p>Scatter dot plots of values for statistics that distinguish focal deletions affecting common frag...
A variety of models have been proposed to explain regions of recurrent somatic copy number alteratio...
<p>A patient with multiple tumors was considered abnormal by a given marker if the aberration was se...
<p>−log10 (p-values) are given for amplification and deletion regions respectively. The dashed green...
<p>(a) Regions of amplification in our study (red circle) were also found in previous studies of oth...
A variety of models have been proposed to explain regions of recurrent somatic copy number alteratio...
<p>Boxplots show the CNA frequency distributions among tumor samples in 10 randomly selected cancer ...
Prostate cancer cell lines provide ideal in vitro systems for the identification and analysis of pro...
SummaryLittle is understood about the occurrence of somatic genomic alterations in normal tissues an...
<p>(A) Histogram of frequency of amplification (red) or deletion (blue) of genome sequences of leuko...
Determining how somatic copy-number alterations (SCNAs) promote cancer is an important goal. We char...
a) Barplot showing the number of samples per tumour and colored by WGD clonality status with clonal ...
a) Barplots showing the proportion of the genome affected by MSAI in each tumour sample in the pan-c...
<p>Cases are grouped by mutation and SCNA status. Top panel: only significant clustering genes are s...
<p>Panel A shows box plots with the distribution of tumors (n = 31) according to the percentage of t...
<p>Scatter dot plots of values for statistics that distinguish focal deletions affecting common frag...
A variety of models have been proposed to explain regions of recurrent somatic copy number alteratio...
<p>A patient with multiple tumors was considered abnormal by a given marker if the aberration was se...
<p>−log10 (p-values) are given for amplification and deletion regions respectively. The dashed green...
<p>(a) Regions of amplification in our study (red circle) were also found in previous studies of oth...
A variety of models have been proposed to explain regions of recurrent somatic copy number alteratio...
<p>Boxplots show the CNA frequency distributions among tumor samples in 10 randomly selected cancer ...
Prostate cancer cell lines provide ideal in vitro systems for the identification and analysis of pro...
SummaryLittle is understood about the occurrence of somatic genomic alterations in normal tissues an...