The distribution of DNA methylation among included versus skipped exons in male gametes.

<p>The plots illustrate that exons included in transcription are more highly methylated than those skipped during transcription for the first, internal, and last exons. The methylation level (weighted methylation level) around exons was calculated by dividing the regions +/− 200 bp within the start and end site of either included exons or skipped exons into 20 equal intervals for internal exons. For first and last exons, regions of +/− 150 bp were divided into 15 equal intervals. Solid line: included exons; dotted line: skipped exons.