<p>(A) Structures of CF0002 and new analogs. (B) Inclusions formed in cells treated with indicated N-acylhydrazone at specified concentrations. Experimental conditions and data collection were the same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0185783#pone.0185783.g001" target="_blank">Fig 1C</a>. Note the highest concentration tested for SF3, SF5 and SF6 was 75 μM, 50 μM and 50 μM, respectively, due to their limited solubility. The 0 μM cultures contained 1% DMSO in their media. A scale bar is at the bottom.</p
The phenylhydrazone RDR-1 is endowed with moderate activity as F508del-CFTR corrector; nevertheless,...
The cystic fibrosis transmembrane conductance regulator (CFTR) protein is a cAMP-regulated epithelia...
Multicomponent solid forms of the BCS class IV drug furosemide (FSM) were obtained upon liquid assis...
Sexually transmitted Chlamydia trachomatis is an extremely common infection and often leads to serio...
<p>HeLa cells were infected with RFP/iGFP-L2r at an MOI of 0.2 inclusion-forming unit per cell. Chem...
Chlamydia trachomatis infection is the most commonly reported sexually transmitted disease in the Un...
The purpose of this study was to evaluate the anti-chlamydia1 activities in vitro of liposome-encaps...
Salicylidene acylhydrazides belong to a class of compounds shown to inhibit bacterial type III secre...
<p>A). Efficacy of niclosamide and sixteen structurally related compounds against HRV1A infection of...
The obligate intracellular pathogen <i>Chlamydia pneumoniae</i> remains a difficult target for antim...
<p>(<i>A</i>) Planar structure of compound 82879. (<i>B</i>) Structural analogues from the small mol...
ABSTRACT: One of the major therapeutic strategy in cystic fibrosis aims at developing modulators of ...
<div><p>The salicylidene acylhydrazide (SA) compounds have exhibited promising microbicidal properti...
Two unanswered questions in the field of Chlamydia are 1) How does the inclusion grow over time? and...
Chlamydia trachomatis is an obligate intracellular bacterium that infects over 100 million people gl...
The phenylhydrazone RDR-1 is endowed with moderate activity as F508del-CFTR corrector; nevertheless,...
The cystic fibrosis transmembrane conductance regulator (CFTR) protein is a cAMP-regulated epithelia...
Multicomponent solid forms of the BCS class IV drug furosemide (FSM) were obtained upon liquid assis...
Sexually transmitted Chlamydia trachomatis is an extremely common infection and often leads to serio...
<p>HeLa cells were infected with RFP/iGFP-L2r at an MOI of 0.2 inclusion-forming unit per cell. Chem...
Chlamydia trachomatis infection is the most commonly reported sexually transmitted disease in the Un...
The purpose of this study was to evaluate the anti-chlamydia1 activities in vitro of liposome-encaps...
Salicylidene acylhydrazides belong to a class of compounds shown to inhibit bacterial type III secre...
<p>A). Efficacy of niclosamide and sixteen structurally related compounds against HRV1A infection of...
The obligate intracellular pathogen <i>Chlamydia pneumoniae</i> remains a difficult target for antim...
<p>(<i>A</i>) Planar structure of compound 82879. (<i>B</i>) Structural analogues from the small mol...
ABSTRACT: One of the major therapeutic strategy in cystic fibrosis aims at developing modulators of ...
<div><p>The salicylidene acylhydrazide (SA) compounds have exhibited promising microbicidal properti...
Two unanswered questions in the field of Chlamydia are 1) How does the inclusion grow over time? and...
Chlamydia trachomatis is an obligate intracellular bacterium that infects over 100 million people gl...
The phenylhydrazone RDR-1 is endowed with moderate activity as F508del-CFTR corrector; nevertheless,...
The cystic fibrosis transmembrane conductance regulator (CFTR) protein is a cAMP-regulated epithelia...
Multicomponent solid forms of the BCS class IV drug furosemide (FSM) were obtained upon liquid assis...