Additional file 6: Figure S6. of Non-digestible oligosaccharides directly regulate host kinome to modulate host inflammatory responses without alterations in the gut microbiota

Effects of inulin and scFOS on metagenome functional content of LPS-treated mouse pups. (A) Relative abundance (%) of COG functional categories in colonic contents of P10 pups. Metagenome functional content was predicted from 16S rRNA gene sequences using PICRUSt. Stcvhatistical testing was done using one-way ANOVAs. (B) Comparison of the mean relative abundance (%) of COG functional categories between colonic microbiota of mouse pups with (All LPS groups) and without (Control) LPS-induced endotoxemia (n = 4-5/group, Welch’s two-sided t-test, Welch’s inverted 95% CI, Benjamini-Hochberg FDR correction). (JPEG 236 kb