Maximum-likelihood inferred phylogeny of carotenoid cyclase/synthase proteins.

<p>Accessions of sequences retrieved from the public databases are indicated in parenthesis as Proteins OGS1.0 numbers for <i>My</i>. <i>persicae</i> (Clone G006), <i>Mayetiola destructor</i> gene model number, or NCBI number elsewhere. Phylloxeridae including <i>Daktulosphaira</i> an<i>d Phylloxera</i> species are boxed in solid lines and Adelgidae is boxed in dotted lines. Three stem gall-inducing <i>Phylloxera</i> species are highlighted in yellow. Carotenoid cyclase/synthases in red, blue and green shown here form tail-to-tail pairs, respectively, with <i>Ac</i>. <i>pisum</i> desaturase with same color shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0185484#pone.0185484.g004" target="_blank">Fig 4</a>, based on their gene locations in the genome. Branches with bootstrap (1000 replicates) support values ≥ 70% are labelled. The tree is rooted with bacterial homologs and is drawn to scale, with branch lengths measured in the number of substitutions per site.