<p>The power of curves as a function of sample sizes of 11 statistics for collectively testing the association of all rare variants in the gene with 10 traits with moderate correlations for the scenario 1 at the significance level <i>α</i> = 0.05.</p
<p>Each box corresponds to a different proportion of causal variants involved in the relationship be...
<p>Power estimates for BOMP, VT, SKAT, KBAC (KBAC1P = minor allele frequency defined as , KBAC5P = m...
<p>Power curves under Dominant AND Dominant with two genes including rare variants only.</p
<p>Power curves as a function of sample sizes under Dominant OR Dominant with two genes including ra...
A sample size with sufficient statistical power is critical to the success of genetic association st...
*<p>Abbreviations and definitions are given in <a href="http://www.plosone.org/article/info:doi/10.1...
The power of a statistical test is the probability that it will yield a statistically significant re...
<p>The color of the line represents the proportion of total variance capture by the risk score, with...
<p>Proportion of causal variants reaching significance as a function of the average effect and propo...
<p>Areas below the ROC curves for different proportions of altered genes (<i>γ</i>), varying from 0....
<p>Power is measured across one hundred simulations of phenotypic effects at each of 24 human gene l...
<p>Graphs were plotted for CV value thresholds t = 0.5 t = 0.1, t = 0.05 and t = 0.01. Percentage of...
<p>Number of genes with only rare variants significantly associated with 46 traits.</p
<p>Number of alleles per locus in different populations studied (Allelic Richness).</p
<p>The calculated power with varying degrees of genetic heterogeneities (<i>R</i>) ranging from 0.01...
<p>Each box corresponds to a different proportion of causal variants involved in the relationship be...
<p>Power estimates for BOMP, VT, SKAT, KBAC (KBAC1P = minor allele frequency defined as , KBAC5P = m...
<p>Power curves under Dominant AND Dominant with two genes including rare variants only.</p
<p>Power curves as a function of sample sizes under Dominant OR Dominant with two genes including ra...
A sample size with sufficient statistical power is critical to the success of genetic association st...
*<p>Abbreviations and definitions are given in <a href="http://www.plosone.org/article/info:doi/10.1...
The power of a statistical test is the probability that it will yield a statistically significant re...
<p>The color of the line represents the proportion of total variance capture by the risk score, with...
<p>Proportion of causal variants reaching significance as a function of the average effect and propo...
<p>Areas below the ROC curves for different proportions of altered genes (<i>γ</i>), varying from 0....
<p>Power is measured across one hundred simulations of phenotypic effects at each of 24 human gene l...
<p>Graphs were plotted for CV value thresholds t = 0.5 t = 0.1, t = 0.05 and t = 0.01. Percentage of...
<p>Number of genes with only rare variants significantly associated with 46 traits.</p
<p>Number of alleles per locus in different populations studied (Allelic Richness).</p
<p>The calculated power with varying degrees of genetic heterogeneities (<i>R</i>) ranging from 0.01...
<p>Each box corresponds to a different proportion of causal variants involved in the relationship be...
<p>Power estimates for BOMP, VT, SKAT, KBAC (KBAC1P = minor allele frequency defined as , KBAC5P = m...
<p>Power curves under Dominant AND Dominant with two genes including rare variants only.</p