miR-27a increases tube formation of HLECs on Matrigel and promotes migration of HLECs.

<p>(A and B) Representative phase-contrast photographs and quantification of capillary-like tube formation in control or miR-27a mimic transfected HLECs (A) and control or miR-27a inhibitor transfected HLECs (B). Tube formation was quantified by the length of tubes. (C and D) Representative phase-contrast photographs and quantification of Transwell cell migration of control or miR-27a mimic transfected HLECs (C) and control or miR-27a inhibitor transfected HLECs (D). (E and F) Real-time qPCR analysis of Prox-1 expression in miR-27a mimic transfected HLECs or control (E) and miR-27a inhibitor transfected HLECs or control (F). Bars, means ± SD from 3 independent experiments. <i>*P < 0</i>.<i>05</i>, <i>**P < 0</i>.<i>01</i>, versus expression in negative control.