Comparing cell activity, LDH release and viability of ARPE-19 cells cultured on flat, round and v-shaped well plates at 1 x 10⁴ cells per well density over 5 days and at fixed growth volume and fixed growth surface area.

<p>Group A: Mitochondrial activity of ARPE-19 cells cultured at 1 x 10⁴ cells per well density; A1) cell activity cultured on flat, round and v-shaped well plates at FV and relative to flat well plates; A2) cell activity cultured on flat, round and v-shaped well plates at FSA and relative to flat well plates. Group B: LDH release measurements of RPE-19 cells cultured at 1 x 10⁴ cells per well density; B1) LDH release on flat, round and v-shaped plates at FV and relative to flat; B2) LDH release on flat, round and v-shaped plates and relative to flat at FSA. Group C: cell viability/ml of ARPE-19 cells cultured at 1 x 10⁴ cells per well density; C1) flat, round and v-shaped cell viability relative to flat well plates at FV; C2) flat, round and v-shaped cell viability relative to flat well plates at FSA. Data are represented as mean + SD of three independent repeats (n = 3). Any significant difference in results is shown as <i>p</i> ≤ 0.05*, <i>p</i> ≤ 0.01**, <i>p</i> ≤ 0.001***.