<p>Blood-derived and <i>in vitro</i> generated Th17 cells were infected with HIV for 24 hours. <b>(A)</b> Th17 cells were cultured for 3 days with anti-CD3 and anti-CD28 mAbs. Supernatants were harvested and assayed for secreted IL-17 by ELISA; * p < 0.001, n = 9; ** p = 0.045, n = 9. Data shown are mean ± SEM. <b>(B)</b> Representative histograms showing intracellular expression of IL-17 in Th17 cells stimulated for 6 hours with PMA and onomycin in the presence of brefeldin A. (<b>C)</b> Summary of the proportion of blood-derived and <i>in vitro</i> generated Th17 cells expressing IL-17 following PMA and ionomycin stimulation is shown with mean frequency indicated; + p = 0.026, n = 9, ++ p = 0.012, n = 5.</p
OBJECTIVE: CD4 T-cell depletion is central to HIV pathogenesis. However, the relative impact of HIV ...
<p>Circulating Th17 cells were isolated from HIV-seronegative or untreated HIV-infected individuals ...
International audienceAmong CD4+ T-cells, T helper 17 (Th17) cells play a sentinel role in the defen...
Summary: The crosstalk between intestinal epithelial cells (IECs) and Th17-polarized CD4+ T cells is...
<p>CD-14 derived PBMC isolated from HIV infected patients vaccinated with an anti-p17 vaccine were s...
There is an increasing body of evidence showing that TH17 cells constitute a novel TH cell lineage [...
Interleukin-17 (IL-17) is a pro-inflammatory cytokine that is mainly produced by CD4 + T cells. The ...
Little is known about the manipulation of IL-17 producing CD4+ T cells (T(H)17) on a per-cell basis ...
HIV infection causes a profound depletion of gut derived Th17 cells, contributing to loss of mucosal...
Little is known about the manipulation of IL-17 producing CD4+ T cells (TH17) on a per-cell basis in...
Th17 cells are enriched in the gut mucosa and play a critical role in maintenance of the mucosal bar...
Little is known about the manipulation of IL-17 producing CD4+ T cells (TH17) on a per-cell basis in...
<p>Th1 and Th17 cells were assessed after 5 h PMA/ionomycin stimulation of fresh isolated CD4 T cell...
We investigated the effects of human immunodeficiency type-1 virus (HIV-1) matrix protein p17 on fr...
Background: Failure to normalize CD4+ T-cell count despite effective antiretroviral therapy (ART) is...
OBJECTIVE: CD4 T-cell depletion is central to HIV pathogenesis. However, the relative impact of HIV ...
<p>Circulating Th17 cells were isolated from HIV-seronegative or untreated HIV-infected individuals ...
International audienceAmong CD4+ T-cells, T helper 17 (Th17) cells play a sentinel role in the defen...
Summary: The crosstalk between intestinal epithelial cells (IECs) and Th17-polarized CD4+ T cells is...
<p>CD-14 derived PBMC isolated from HIV infected patients vaccinated with an anti-p17 vaccine were s...
There is an increasing body of evidence showing that TH17 cells constitute a novel TH cell lineage [...
Interleukin-17 (IL-17) is a pro-inflammatory cytokine that is mainly produced by CD4 + T cells. The ...
Little is known about the manipulation of IL-17 producing CD4+ T cells (T(H)17) on a per-cell basis ...
HIV infection causes a profound depletion of gut derived Th17 cells, contributing to loss of mucosal...
Little is known about the manipulation of IL-17 producing CD4+ T cells (TH17) on a per-cell basis in...
Th17 cells are enriched in the gut mucosa and play a critical role in maintenance of the mucosal bar...
Little is known about the manipulation of IL-17 producing CD4+ T cells (TH17) on a per-cell basis in...
<p>Th1 and Th17 cells were assessed after 5 h PMA/ionomycin stimulation of fresh isolated CD4 T cell...
We investigated the effects of human immunodeficiency type-1 virus (HIV-1) matrix protein p17 on fr...
Background: Failure to normalize CD4+ T-cell count despite effective antiretroviral therapy (ART) is...
OBJECTIVE: CD4 T-cell depletion is central to HIV pathogenesis. However, the relative impact of HIV ...
<p>Circulating Th17 cells were isolated from HIV-seronegative or untreated HIV-infected individuals ...
International audienceAmong CD4+ T-cells, T helper 17 (Th17) cells play a sentinel role in the defen...