<p>PA103 (MOI 4) was added at 0 h, then IDR-1002 (50 μM) or LL-37 (3 μM) was added at -1 h (A, B) or 0 h (C, D). Samples were collected at 6 h and used for ELISAs for IL-6 (A, C) or IL-8 (B, D). Data represent mean ± SEM from four independent experiments and were analyzed using two-way ANOVA and Dunnett’s multiple comparisons test. *: p ≤ 0.05, **: p ≤ 0.01, ****: p ≤ 0.0001 compared to PA103.</p
<p>In (A) and (B), cells were infected with the different <i>P. aeruginosa</i> strains for 21 hours ...
(A) IL-6 and (B) IL-8 present in the basolateral medium from H441 polarised monolayers before (contr...
ELISA quantitation of human cytokines IL-8 (A), IL-1β (B) and IL-18 (C) released from NHBE cells tre...
<p>Peptide was added to the cells, then supernatants were collected after 24 h for ELISAs. IDR-1002 ...
<p>(A, B) Live <i>P</i>. <i>aeruginosa</i> PA103 (MOI 4) was added to HBE cells at 0 h, IDR-1002 (50...
<p>A549 cells (1 × 10<sup>6</sup> cells/well/mL) were cultured in 12-well plates overnight followed ...
<p>Footnote: Data are presented as median (min–max) ng/ml of secreted IL-8. hHBE: healthy HBE cells;...
<p>Kinetics of IL-8 (A) and IL-6 (B) production by hAEBCs infected with <i>P</i>. <i>aeruginosa</i>....
<p>Cytokine secretion by HBEC exposed to DMA<sup>V</sup> ± <i>P</i>. <i>aeruginosa</i>. n = 4 donors...
<p>Cytokine secretion by HBEC exposed to MMA<sup>III</sup> ± <i>P</i>. <i>aeruginosa</i>. n = 4 dono...
<p>A549 cells (1 × 10<sup>6</sup> cells/well) were cultured in 12-well plates for 24 h, followed by ...
<p>Primary healthy HBE cells were pre-incubated for 18 hours with experimental culture medium (BEGM ...
<p>Supernatants from uninfected and infected macrophages (MOI = 1) were collected at 2, 4, and 6 hpi...
<p>In (A), representative agarose gels of RT-PCR assays in which A549 cells were treated or not with...
<p>(<b>A</b>) and (<b>B</b>) Primary healthy (h) and CF (cf) HBE cells were pre-incubated for 18 hou...
<p>In (A) and (B), cells were infected with the different <i>P. aeruginosa</i> strains for 21 hours ...
(A) IL-6 and (B) IL-8 present in the basolateral medium from H441 polarised monolayers before (contr...
ELISA quantitation of human cytokines IL-8 (A), IL-1β (B) and IL-18 (C) released from NHBE cells tre...
<p>Peptide was added to the cells, then supernatants were collected after 24 h for ELISAs. IDR-1002 ...
<p>(A, B) Live <i>P</i>. <i>aeruginosa</i> PA103 (MOI 4) was added to HBE cells at 0 h, IDR-1002 (50...
<p>A549 cells (1 × 10<sup>6</sup> cells/well/mL) were cultured in 12-well plates overnight followed ...
<p>Footnote: Data are presented as median (min–max) ng/ml of secreted IL-8. hHBE: healthy HBE cells;...
<p>Kinetics of IL-8 (A) and IL-6 (B) production by hAEBCs infected with <i>P</i>. <i>aeruginosa</i>....
<p>Cytokine secretion by HBEC exposed to DMA<sup>V</sup> ± <i>P</i>. <i>aeruginosa</i>. n = 4 donors...
<p>Cytokine secretion by HBEC exposed to MMA<sup>III</sup> ± <i>P</i>. <i>aeruginosa</i>. n = 4 dono...
<p>A549 cells (1 × 10<sup>6</sup> cells/well) were cultured in 12-well plates for 24 h, followed by ...
<p>Primary healthy HBE cells were pre-incubated for 18 hours with experimental culture medium (BEGM ...
<p>Supernatants from uninfected and infected macrophages (MOI = 1) were collected at 2, 4, and 6 hpi...
<p>In (A), representative agarose gels of RT-PCR assays in which A549 cells were treated or not with...
<p>(<b>A</b>) and (<b>B</b>) Primary healthy (h) and CF (cf) HBE cells were pre-incubated for 18 hou...
<p>In (A) and (B), cells were infected with the different <i>P. aeruginosa</i> strains for 21 hours ...
(A) IL-6 and (B) IL-8 present in the basolateral medium from H441 polarised monolayers before (contr...
ELISA quantitation of human cytokines IL-8 (A), IL-1β (B) and IL-18 (C) released from NHBE cells tre...