MOESM3 of The macrophage C-type lectin receptor CLEC5A (MDL-1) expression is associated with early plaque progression and promotes macrophage survival

Additional file 3: Figure S3. MDL-1 and M1 subtype macrophage marker iNOS colocalize in early advanced ldlr−/− mice atherosclerotic lesion and both reduce in regressive plaque. Immunofluorescent costaining of MDL-1 (green) and iNOS (red) in aortic sinus plaques in a progressive (ldlr−/− mice fed a 8-week HFD) or regressive (ldlr−/− mice fed a 8-week HFD and then switched to 4-week chow diet) environment. Areas of colocalization are exhibited in yellow in the merged image. Images are representative of at least 3 mice