Effects of the 5-HT_2CR antagonist and the endogenous ghrelin enhancer on cumulative food intake and the plasma corticosterone level in aged female mice exposed to novelty stress.

<p>5-HT_2CR antagonists, SB242084 (6 mg/kg, PO) or RKT(1000 mg/kg, PO) was administered immediately after stress exposure. (A) Cumulative food intake (1 h and 3 h) and (B) plasma corticosterone levels (3 h) after stress exposure was determined in 18 h fasted aged female mice. Data are presented as the mean ± SEM (n = 5–10). ###, p < 0.001 vs. control group, ***, p < 0.001 vs. novelty stress group.