Additional file 2: Figure S2. of Coevolution of Siglec-11 and Siglec-16 via gene conversion in primates

Phylogenetic relationships of the A/A’ regions of SIGLEC11 and SIGLEC16. The partial sequence of bonobo SIGLEC11 was obtained previously (GenBank accession no. AB211392; [11]) and used in the tree construction. The tree topology is identical to that shown in Fig. 2A, with the exception of genes of the genus Pan. As for the lineage of the genus Pan, bonobo SIGLEC11 is most closely related to chimpanzee SIGLEC11 but the genes of genus Pan form a cluster in the tree. This suggests that gene conversion between SIGLEC11 and SIGLEC16 occurred before the divergence of chimpanzee and bonobo in the lineage of the genus Pan. Numbers on the phylogenetic tree represent bootstrap values based on 1000 replications. Hsa, Homo sapiens; Ptr, Pan troglodytes; Ppa, Pan paniscus; Ggo, Gorilla gorilla; Hla, Hylobates lar; Pan, Papio anubis; Cja, Callithrix jacchus. (PDF 45 kb