Functions ranked based on functional variability of genes.

<p>Top 10 gained (green) and lost (red) functions are shown, along with <i>Δ</i>_<i>f</i>, <i>Δ</i>_<i>f</i> divided (normalized) by the number of genes annotated by the function, followed by the sample shuffling, and the log fold change, which is the log ratio of the average number of expressed genes annotated by <i>f</i> in cancer and normal samples.