Jagged1 and Notch3 genes were upregulated in immortalized human dystrophic myogenic cells.

<p>(A and B) The expression of Notch ligands Jagged1 (JAG1), Jagged2 (JAG2), and deltaless-like1 (DLL1) (A) and Notch receptors Notch1, Notch2, and Notch3 (B) in seven non-dystrophic and six dystrophic myogenic cell lines was analyzed by qRT-PCR. Cells were cultured in growth medium pmGM. The amounts of mRNA were normalized to control B2M mRNA value. The means and standard deviations were estimated from four independent reactions for each cell line. Data were statistically analyzed using Student’s <i>t</i>-test. P values of non-dystrophic myogenic cells and dystrophic myogenic cells are shown at the tops of panels.