Evaluation of Genetic Parameters of 22 STR loci in two Minorities Population from Yunnan Province of China

A total of 22 Short Tandem Repeat (STR) loci (include 3 Expanded U.S. Core Loci D2S441, D22S1045, D10S1248 and 19 non-CODIS STR D1S1627, D3S4529, D17S974, D6S1017, D4S2408, D9S2157, D6S474, D1GATA113, D18S853, D20S482, D14S1434, D20S1082, D17S1301, D12ATA63, D1S1677, D11S4463, D9S1122, D2S1776, D5S2500) were analyzed in two minorities population from Yunnan Province of China with 298 (Wa200, Bai98) unrelated individuals. The allele frequency distribution and forensic parameters of the two populations were reported in this paper. The results show these 22 STR loci have high or medium power of discrimination and probabilities of exclusion. The Hardy–Weinberg Equilibrium of each locus were tested. The genetic distances (i.e., Fst) among the two population and other Chinese populations were estimated. The results showed that these loci are available in forensic genetics and may prove useful in both human identification and kinship analysis