Optical microscopy and AFM images of scr-MDA and sh-MDA cells.

<p>AFM images were obtained in tapping topography (A-D for scr-MDA and G-J for sh-MDA) and amplitude modes (E for scr-MDA and K for sh-MDA). Fig 4A presents topographical parameters of a complete scr-MDA cell. Fig 4E presents amplitude image. Fig 4G presents topographical parameters of complete sh-MDA cell, and Fig 4K presents amplitude image. Parameters of the pictures are 50.0 μm x 50.0 μm (Fig 4A, E, G and K); 30.0 μm x 30.0 μm (Fig 4B and H); 15.0 μm x 15.0 μm (Fig 4C and I); 10.0 μm x 10.0 μm (Fig 4D and J). All images have a resolution of 512 x 512 pixels. The height of the cell is expressed in color scale (right bar). White arrows in Figs 4I and J indicate pore-like structures. Optical images (Fig 4F and L) have a magnification of 200x.