Additional file 17: Figure S7. of A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis

Gene expression influenced by HBV integration. For the recurrent host genes, the gene expression is compared between samples with and without integration. Two recurrent host genes, (A) KMT2B and (B) ARAP2, show gene expression changes induced by HBV integrations. P value is measured by the Student t-test. (C) Differentially expressed genes between tumors with and without HBV-KMT2B integration. A total of 139 genes were over-expressed in the tumors with HBV-KMT2B integration while 32 were under-expressed. The list of the top 20 in over-expressed (red) and top 5 under expressed (green) enriched GO terms within each gene set is shown. (TIF 1420 kb