Regional-association plot for rs71404070 with rotator cuff injury.

<p>Tested SNPs are arranged by genomic position on chromosome 16 (x-axis) in a 2Mb window around the lead SNP rs71404070, including the locus where our association signal is present. The y-axis indicates -log₁₀ p-values for association with rotator cuff injury for each SNP. The top group of SNPs are located in the intergenic region between <i>LOC729159</i> and <i>cadherin8</i> (<i>CDH8</i>). The purple diamond represents the lead SNP rs71404070. The color of dots representing flanking SNPs indicates their linkage disequilibrium (R²) with the lead SNP as indicated in the heat map color key. The grey dots represent SNPs that lack R² information in 1000genomes or HapMap. Blue vertical lines show the recombination rate at specific genomic positions and approximate locus boundaries.