Additional file 2: Figure S1. of Evaluation of epidermal growth factor receptor signaling effects in gastric cancer cell lines by detailed motility-focused phenotypic characterization linked with molecular analysis

Morphological differences in MKN1 cells after treatment with EGF and/or cetuximab. Denoted are hourly time-lapse microscopy movies of MKN1 cells with different treatments: untreated, EGF (5 ng/ml), EGF (5 ng/ml) + cetuximab (1 μg/ml) and cetuximab (1 μg/ml). Additionally, images of Hs746T cells after 4 h treatment are shown. The arrowheads indicate filopodia (1) and lamellipodia formation (2). Scale bar = 50 μm. (PDF 366 kb