Upregulation of s(P)RR, prorenin and activated prorenin protein levels in the plasma of PDR patients.

<p>Protein levels of s(P)RR (A), prorenin (B), and activated prorenin (C) in the plasma of the non-DM and PDR subjects. Black symbols indicate individual samples. n = 20 in each group, **<i>p</i> < 0.01, Student’s t test. (D) Correlation between s(P)RR and prorenin was not detected in the plasma of patients with PDR (n = 20, Spearman rank correlation).