Differential expression of genes in the cell cycle pathway.

<p>Differential expression of genes in the cell cycle pathway (hsa04110, upper panel) and DNA replication (hsa03030, lower panel) for COL6-RD dominant negative vs. null (lower panel). Log₂ fold change is plotted for each gene in the pathway (positive values reflect increased expression in the dominant negative mutants). Genes with significant differential expression (FDR-adjusted p-value was <0.05) are marked with an *.