Additional file 4: Table S3. of Leishmania infantum 5’-Methylthioadenosine Phosphorylase presents relevant structural divergence to constitute a potential drug target

MOESM3 of Predictive classification models and targets identification for betulin derivatives as Leishmania donovani inhibitors

Yuezhou Zhang (3457394)
Henri Xhaard (467313)
Leo Ghemtio (467312)

August 2018

Additional file 3: Fig. S1. Full pharmacological network of Leishmania donovani Betulin derivatives ...

Additional file 2: of Extracellular release of virulence factor major surface protease via exosomes in Leishmania infantum promastigotes

Skye Marshall (5424758)
Patrick Kelly (471660)
Brajesh Singh (4342810)
R. Marshall Pope (1696246)
Peter Kim (636981)
Bayan Zhanbolat (5424761)
Mary Wilson (62087)
Chaoqun Yao (3410480)

June 2018

Figure S2. Alignment of all 17 proteins identified. The first four proteins are examples of previous...

Additional file 4: of Exploiting genetic polymorphisms in metabolic enzymes for rapid screening of Leishmania infantum genotypes

Marcello Ceccarelli (522939)
Aurora Diotallevi (3569489)
Francesca Andreoni (4030070)
Fabrizio Vitale (3569492)
Luca Galluzzi (144241)
Mauro Magnani (120149)

November 2018

Figure S3. Partial sequences of qPCR-MEint amplification products from clinical samples. Electropher...

Additional file 3: Table S2. of Leishmania infantum 5’-Methylthioadenosine Phosphorylase presents relevant structural divergence to constitute a potential drug target

Hela Abid (4705747)
Emna Harigua-Souiai (4705753)
Thouraya Mejri (4705750)
Mourad Barhoumi (437178)
Ikram Guizani (564611)

December 2017

C-scores of the five models generated by I-TASSER for LiMTAP and TbMTAP. The first model was retaine...

Additional file 1: Figure S1. of Leishmania infantum 5’-Methylthioadenosine Phosphorylase presents relevant structural divergence to constitute a potential drug target

Hela Abid (4705747)
Emna Harigua-Souiai (4705753)
Thouraya Mejri (4705750)
Mourad Barhoumi (437178)
Ikram Guizani (564611)

December 2017

Chemical structure of MTA and HETA, docked in HuMTAP, LiMTAP and TbMTAP active sites. (PPTX 66 kb

Additional file 6: Figure S2. of Leishmania infantum 5’-Methylthioadenosine Phosphorylase presents relevant structural divergence to constitute a potential drug target

Hela Abid (4705747)
Emna Harigua-Souiai (4705753)
Thouraya Mejri (4705750)
Mourad Barhoumi (437178)
Ikram Guizani (564611)

December 2017

Alignment of LiMTAP and TbMTAP 3D models on the Human crystal structure (PDB: 1CG6). HuMTAP, LiMTAP ...

Additional file 2: Table S1. of Leishmania infantum 5’-Methylthioadenosine Phosphorylase presents relevant structural divergence to constitute a potential drug target

Hela Abid (4705747)
Emna Harigua-Souiai (4705753)
Thouraya Mejri (4705750)
Mourad Barhoumi (437178)
Ikram Guizani (564611)

December 2017

Taxonomy blast reports for MEME motifs. Organism, blast name, score, number of hits and organism des...

Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting Leishmania eukaryotic translation initiation factor 4A

Harigua-Souiai, Emna
Abdelkrim, Yosser Zina
Bassoumi-Jamoussi, Imen
Zakraoui, Ons
Bouvier, Guillaume
Essafi-Benkhadir, Khadija,
Banroques, Josette
Desdouits, Nathan
Munier-Lehmann, Hélène
Barhoumi, Mourad
Tanner, N. Kyle
Nilges, Michael
Blondel, Arnaud
Guizani, Ikram

January 2018

International audienceLeishmaniases are neglected parasitic diseases in spite of the major burden th...

Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting Leishmania eukaryotic translation initiation factor 4A.

Emna Harigua-Souiai
Yosser Zina Abdelkrim
Imen Bassoumi-Jamoussi
Ons Zakraoui
Guillaume Bouvier
Khadija Essafi-Benkhadir
Josette Banroques
Nathan Desdouits
Hélène Munier-Lehmann
Mourad Barhoumi
N Kyle Tanner
Michael Nilges
Arnaud Blondel
Ikram Guizani

January 2018

Leishmaniases are neglected parasitic diseases in spite of the major burden they inflict on public h...

MOESM1 of Homology modelling, molecular docking, and molecular dynamics simulations reveal the inhibition of Leishmania donovani dihydrofolate reductase-thymidylate synthase enzyme by Withaferin-A

Bharadwaja Vadloori (5107283)
A. Sharath (5107289)
N. Prabhu (5107292)
Radheshyam Maurya (5107286)

April 2018

Additional file 1: Figure S1. The structures of ligands: (A) Withaferin-A, (B) Methotrexate, (C) DHF...

Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting <i>Leishmania</i> eukaryotic translation initiation factor 4A

Emna Harigua-Souiai (4705753)
Yosser Zina Abdelkrim (4778700)
Imen Bassoumi-Jamoussi (4778697)
Ons Zakraoui (3477566)
Guillaume Bouvier (795812)
Khadija Essafi-Benkhadir (267238)
Josette Banroques (4778703)
Nathan Desdouits (4778694)
Hélène Munier-Lehmann (399503)
Mourad Barhoumi (437178)
N. Kyle Tanner (7344)
Michael Nilges (88295)
Arnaud Blondel (402860)
Ikram Guizani (564611)

January 2018

<div><p>Leishmaniases are neglected parasitic diseases in spite of the major burden they inflict on ...

Additional file 1: of Genome-wide mapping of 5-hydroxymethyluracil in the eukaryote parasite Leishmania

Fumiko Kawasaki (229889)
Dario Beraldi (121970)
Robyn Hardisty (3703357)
Gordon McInroy (3561587)
Pieter van Delft (1608421)
Shankar Balasubramanian (9301)

January 2017

The datasets supporting the conclusions of this article as well as experimental designs and protocol...

Additional file 2: of 4-Phenyl-1,3-thiazole-2-amines as scaffolds for new antileishmanial agents

Carina Rodrigues (5078207)
Paloma dos Santos (5735537)
Marcela da Costa (5735543)
Thais Pavani (5735546)
Patrícia Xander (137425)
Mariana Geraldo (5735555)
Ana Mengarda (5735558)
Josué de Moraes (505160)
Daniela Rando (5735561)

September 2018

Structure-Activity Relationships. (a) CLogP versus Biological Activity Graphic. Parabolic Correlatio...

Additional file 1: Figure S1. of Identification of internalin-A-like virulent proteins in Leishmania donovani

Ishita Mukherjee (3425903)
Abhijit Chakraborty (547124)
Saikat Chakrabarti (5065)

October 2016

Plot of docking scores against ligand root mean square deviation (l-RMSD) between the crystal comple...

Additional file 5: of 4-Phenyl-1,3-thiazole-2-amines as scaffolds for new antileishmanial agents

Carina Rodrigues (5078207)
Paloma dos Santos (5735537)
Marcela da Costa (5735543)
Thais Pavani (5735546)
Patrícia Xander (137425)
Mariana Geraldo (5735555)
Ana Mengarda (5735558)
Josué de Moraes (505160)
Daniela Rando (5735561)

September 2018

GPQF-03, GPQF-04, and GPQF-05 best docking poses at S-methyl-5-thioadenosine phosphorylase (1CG6). (...

MOESM3 of Predictive classification models and targets identification for betulin derivatives as Leishmania donovani inhibitors

Yuezhou Zhang (3457394)
Henri Xhaard (467313)
Leo Ghemtio (467312)

August 2018

Additional file 3: Fig. S1. Full pharmacological network of Leishmania donovani Betulin derivatives ...

Additional file 2: of Extracellular release of virulence factor major surface protease via exosomes in Leishmania infantum promastigotes

Skye Marshall (5424758)
Patrick Kelly (471660)
Brajesh Singh (4342810)
R. Marshall Pope (1696246)
Peter Kim (636981)
Bayan Zhanbolat (5424761)
Mary Wilson (62087)
Chaoqun Yao (3410480)

June 2018

Figure S2. Alignment of all 17 proteins identified. The first four proteins are examples of previous...

Additional file 4: of Exploiting genetic polymorphisms in metabolic enzymes for rapid screening of Leishmania infantum genotypes

Marcello Ceccarelli (522939)
Aurora Diotallevi (3569489)
Francesca Andreoni (4030070)
Fabrizio Vitale (3569492)
Luca Galluzzi (144241)
Mauro Magnani (120149)

November 2018

Figure S3. Partial sequences of qPCR-MEint amplification products from clinical samples. Electropher...

Additional file 3: Table S2. of Leishmania infantum 5’-Methylthioadenosine Phosphorylase presents relevant structural divergence to constitute a potential drug target

Hela Abid (4705747)
Emna Harigua-Souiai (4705753)
Thouraya Mejri (4705750)
Mourad Barhoumi (437178)
Ikram Guizani (564611)

December 2017

C-scores of the five models generated by I-TASSER for LiMTAP and TbMTAP. The first model was retaine...

Additional file 1: Figure S1. of Leishmania infantum 5’-Methylthioadenosine Phosphorylase presents relevant structural divergence to constitute a potential drug target

Hela Abid (4705747)
Emna Harigua-Souiai (4705753)
Thouraya Mejri (4705750)
Mourad Barhoumi (437178)
Ikram Guizani (564611)

December 2017

Chemical structure of MTA and HETA, docked in HuMTAP, LiMTAP and TbMTAP active sites. (PPTX 66 kb

Additional file 6: Figure S2. of Leishmania infantum 5’-Methylthioadenosine Phosphorylase presents relevant structural divergence to constitute a potential drug target

Hela Abid (4705747)
Emna Harigua-Souiai (4705753)
Thouraya Mejri (4705750)
Mourad Barhoumi (437178)
Ikram Guizani (564611)

December 2017

Alignment of LiMTAP and TbMTAP 3D models on the Human crystal structure (PDB: 1CG6). HuMTAP, LiMTAP ...

Additional file 2: Table S1. of Leishmania infantum 5’-Methylthioadenosine Phosphorylase presents relevant structural divergence to constitute a potential drug target

Hela Abid (4705747)
Emna Harigua-Souiai (4705753)
Thouraya Mejri (4705750)
Mourad Barhoumi (437178)
Ikram Guizani (564611)

December 2017

Taxonomy blast reports for MEME motifs. Organism, blast name, score, number of hits and organism des...

Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting Leishmania eukaryotic translation initiation factor 4A

Harigua-Souiai, Emna
Abdelkrim, Yosser Zina
Bassoumi-Jamoussi, Imen
Zakraoui, Ons
Bouvier, Guillaume
Essafi-Benkhadir, Khadija,
Banroques, Josette
Desdouits, Nathan
Munier-Lehmann, Hélène
Barhoumi, Mourad
Tanner, N. Kyle
Nilges, Michael
Blondel, Arnaud
Guizani, Ikram

January 2018

International audienceLeishmaniases are neglected parasitic diseases in spite of the major burden th...

Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting Leishmania eukaryotic translation initiation factor 4A.

Emna Harigua-Souiai
Yosser Zina Abdelkrim
Imen Bassoumi-Jamoussi
Ons Zakraoui
Guillaume Bouvier
Khadija Essafi-Benkhadir
Josette Banroques
Nathan Desdouits
Hélène Munier-Lehmann
Mourad Barhoumi
N Kyle Tanner
Michael Nilges
Arnaud Blondel
Ikram Guizani

January 2018

Leishmaniases are neglected parasitic diseases in spite of the major burden they inflict on public h...

MOESM1 of Homology modelling, molecular docking, and molecular dynamics simulations reveal the inhibition of Leishmania donovani dihydrofolate reductase-thymidylate synthase enzyme by Withaferin-A

Bharadwaja Vadloori (5107283)
A. Sharath (5107289)
N. Prabhu (5107292)
Radheshyam Maurya (5107286)

April 2018

Additional file 1: Figure S1. The structures of ligands: (A) Withaferin-A, (B) Methotrexate, (C) DHF...

Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting <i>Leishmania</i> eukaryotic translation initiation factor 4A

Emna Harigua-Souiai (4705753)
Yosser Zina Abdelkrim (4778700)
Imen Bassoumi-Jamoussi (4778697)
Ons Zakraoui (3477566)
Guillaume Bouvier (795812)
Khadija Essafi-Benkhadir (267238)
Josette Banroques (4778703)
Nathan Desdouits (4778694)
Hélène Munier-Lehmann (399503)
Mourad Barhoumi (437178)
N. Kyle Tanner (7344)
Michael Nilges (88295)
Arnaud Blondel (402860)
Ikram Guizani (564611)

January 2018

<div><p>Leishmaniases are neglected parasitic diseases in spite of the major burden they inflict on ...

Additional file 1: of Genome-wide mapping of 5-hydroxymethyluracil in the eukaryote parasite Leishmania

Fumiko Kawasaki (229889)
Dario Beraldi (121970)
Robyn Hardisty (3703357)
Gordon McInroy (3561587)
Pieter van Delft (1608421)
Shankar Balasubramanian (9301)

January 2017

The datasets supporting the conclusions of this article as well as experimental designs and protocol...

Additional file 2: of 4-Phenyl-1,3-thiazole-2-amines as scaffolds for new antileishmanial agents

Carina Rodrigues (5078207)
Paloma dos Santos (5735537)
Marcela da Costa (5735543)
Thais Pavani (5735546)
Patrícia Xander (137425)
Mariana Geraldo (5735555)
Ana Mengarda (5735558)
Josué de Moraes (505160)
Daniela Rando (5735561)

September 2018

Structure-Activity Relationships. (a) CLogP versus Biological Activity Graphic. Parabolic Correlatio...

Additional file 1: Figure S1. of Identification of internalin-A-like virulent proteins in Leishmania donovani

Ishita Mukherjee (3425903)
Abhijit Chakraborty (547124)
Saikat Chakrabarti (5065)

October 2016

Plot of docking scores against ligand root mean square deviation (l-RMSD) between the crystal comple...

Additional file 5: of 4-Phenyl-1,3-thiazole-2-amines as scaffolds for new antileishmanial agents

Carina Rodrigues (5078207)
Paloma dos Santos (5735537)
Marcela da Costa (5735543)
Thais Pavani (5735546)
Patrícia Xander (137425)
Mariana Geraldo (5735555)
Ana Mengarda (5735558)
Josué de Moraes (505160)
Daniela Rando (5735561)

September 2018

GPQF-03, GPQF-04, and GPQF-05 best docking poses at S-methyl-5-thioadenosine phosphorylase (1CG6). (...

MOESM3 of Predictive classification models and targets identification for betulin derivatives as Leishmania donovani inhibitors

Yuezhou Zhang (3457394)
Henri Xhaard (467313)
Leo Ghemtio (467312)

August 2018

Additional file 3: Fig. S1. Full pharmacological network of Leishmania donovani Betulin derivatives ...

Additional file 2: of Extracellular release of virulence factor major surface protease via exosomes in Leishmania infantum promastigotes

Skye Marshall (5424758)
Patrick Kelly (471660)
Brajesh Singh (4342810)
R. Marshall Pope (1696246)
Peter Kim (636981)
Bayan Zhanbolat (5424761)
Mary Wilson (62087)
Chaoqun Yao (3410480)

June 2018

Figure S2. Alignment of all 17 proteins identified. The first four proteins are examples of previous...

Additional file 4: of Exploiting genetic polymorphisms in metabolic enzymes for rapid screening of Leishmania infantum genotypes

Marcello Ceccarelli (522939)
Aurora Diotallevi (3569489)
Francesca Andreoni (4030070)
Fabrizio Vitale (3569492)
Luca Galluzzi (144241)
Mauro Magnani (120149)

November 2018

Figure S3. Partial sequences of qPCR-MEint amplification products from clinical samples. Electropher...

Additional file 4: Table S3. of Leishmania infantum 5’-Methylthioadenosine Phosphorylase presents relevant structural divergence to constitute a potential drug target

Abstract

Extracted data

Additional file 4: Table S3. of Leishmania infantum 5’-Methylthioadenosine Phosphorylase presents relevant structural divergence to constitute a potential drug target

Abstract

Extracted data

Related items

Related items