<p>T-cell survival graphs for all animals in the IL-7 treatment group. In all plots, an arbitrary, yet common crossing point of 5 BrDU<sup>+</sup> cells/μl of blood is indicated by a dotted line. The clustered administration of IL-7 is indicated on the x-axis by groups of three arrows and the first day of the BrDU injections is also indicated.</p
<p>C57Bl/6 mice were i.p. injected with PBS or IL-7/anti-IL-7 complexes (1 µg rmIL-7 plus 5 µg M25) ...
<p>A) IL-7 (left panel) and soluble IL-7Rα (sCD127; right panel) levels as measured in the sera of p...
<p>(A) Example of pSTAT5 response to IL-7 stimulation measured in whole blood from a healthy donor. ...
<p>(A) Mean levels (± SEM) of cellular proliferation, as measured by expression of the cell-cycling ...
<p>(A) Plasma IL-7 concentrations in IL-7-treated and untreated macaques. IL-7-treated animals recei...
<p>(A) Mean absolute numbers (± SEM) of circulating total, naïve, memory and effector CD4<sup>+</sup...
<p>(<b>A</b>) Bromodeoxyuridine (BrdU) treatment experimental procedure. (<b>B</b>) BrdU positive ce...
<p>CD8 T cells were enriched from C57Bl6/J donors and cultured with a range of IL-7 concentrations. ...
<p>Parameter estimates of Model 1 (effect on proliferation rate only), Model 2 (effect on proliferat...
<p>(A) IL-7 plasma levels were quantified in peripheral blood cells from acutely HCV-infected (light...
<p>Box and whisker plot with outliers showing interquartile range (median bar in intersect between t...
<p>Mean levels (± SEM) of SIV plasma viremia (A) and p27<sub>Gag</sub> antigenemia (B) in untreated ...
IL-7 is a critical component of thymopoiesis in animals and has recently been shown to play an impor...
Abstract Introduction Soluble forms of cytokine receptors can be involved in the endogenous regulati...
IL-7 is an essential cytokine in T-cell development and homeostasis. It binds to the IL-7R receptor,...
<p>C57Bl/6 mice were i.p. injected with PBS or IL-7/anti-IL-7 complexes (1 µg rmIL-7 plus 5 µg M25) ...
<p>A) IL-7 (left panel) and soluble IL-7Rα (sCD127; right panel) levels as measured in the sera of p...
<p>(A) Example of pSTAT5 response to IL-7 stimulation measured in whole blood from a healthy donor. ...
<p>(A) Mean levels (± SEM) of cellular proliferation, as measured by expression of the cell-cycling ...
<p>(A) Plasma IL-7 concentrations in IL-7-treated and untreated macaques. IL-7-treated animals recei...
<p>(A) Mean absolute numbers (± SEM) of circulating total, naïve, memory and effector CD4<sup>+</sup...
<p>(<b>A</b>) Bromodeoxyuridine (BrdU) treatment experimental procedure. (<b>B</b>) BrdU positive ce...
<p>CD8 T cells were enriched from C57Bl6/J donors and cultured with a range of IL-7 concentrations. ...
<p>Parameter estimates of Model 1 (effect on proliferation rate only), Model 2 (effect on proliferat...
<p>(A) IL-7 plasma levels were quantified in peripheral blood cells from acutely HCV-infected (light...
<p>Box and whisker plot with outliers showing interquartile range (median bar in intersect between t...
<p>Mean levels (± SEM) of SIV plasma viremia (A) and p27<sub>Gag</sub> antigenemia (B) in untreated ...
IL-7 is a critical component of thymopoiesis in animals and has recently been shown to play an impor...
Abstract Introduction Soluble forms of cytokine receptors can be involved in the endogenous regulati...
IL-7 is an essential cytokine in T-cell development and homeostasis. It binds to the IL-7R receptor,...
<p>C57Bl/6 mice were i.p. injected with PBS or IL-7/anti-IL-7 complexes (1 µg rmIL-7 plus 5 µg M25) ...
<p>A) IL-7 (left panel) and soluble IL-7Rα (sCD127; right panel) levels as measured in the sera of p...
<p>(A) Example of pSTAT5 response to IL-7 stimulation measured in whole blood from a healthy donor. ...