Additional file 4: Figure S3. of HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma
- Qiuran Xu (4103755)
- Jianfeng Tu (4103758)
- Changwei Dou (3554573)
- Jun Zhang (48506)
- Liu Yang (23752)
- Xin Liu (43569)
- Kefeng Lei (4708894)
- Zhikui Liu (3554570)
- Yufeng Wang (274657)
- Lijie Li (1438762)
- Hangxing Bao (4103752)
- Jiahui Wang (746367)
- Kangsheng Tu (428934)
Publication date
December 2017
DOIAbstract
MG132 restored the protein level of PKM2 induced by HSP90 knockdown. MG-132 was used to inhibit the proteasomal degradation in Hep3B cells. MG-132 treatment led to PKM2 accumulation in the detergent insoluble fraction of the cell lysate. (TIFF 7067Â kb
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