Comparative transcriptome analysis of enthesis and cartilage.

<p>a, Venn diagram depicts the number of annotated genes that were only present in enthesis (70) or cartilage (100) or present in both tissues (13832). b, Volcano plot of all differentially enriched genes detected in the transcriptomes of enthesis (orange) and cartilage (green). Statistically significant enriched genes were marked red. c, List of genes with highest enrichment of gene expression in enthesis (orange) or cartilage (green). d, Protein-protein interaction network for transcription factors and growth factors enriched in cartilage compared to enthesis. Protein-protein interactions were predicted using the database Search Tool for the Retrieval of Interacting Genes/Proteins (STRING). Line thickness indicated strength of data support for protein-protein interaction.