Increased frequencies and absolute numbers of effector memory CD4⁺ T cells in cancer septic animals relative to previously healthy septic controls.

<p>CD4⁺ T cells isolated from splenocytes of previously healthy or cancer septic animals were analyzed by flow cytometry. A, Representative flow plots of CD44 and CD62L expression. Frequencies (B) and absolute numbers (C) of naïve, central memory, and effector memory T cells from previously healthy vs. cancer septic animals. D, Representative flow plots of CD69 and CD25 expression. Frequencies (E) and absolute numbers (F) of CD25⁺ and CD69⁺ CD4⁺ T cells from previously healthy vs. cancer septic animals. n = 11/group. ***p<0.001.