<p><b>(A–B)</b> Upper panel shows representative triple-labeled immunostaining of CD8+CD68+ cells expressing iNOS or Arg1 in the perilesional areas of the ischemic hemisphere at 6 h, and at days 1, 2, 3 and 4 after stroke. Lower panel shows quantification data. <b>(C)</b> Proportion of CD8+CD68+ cells expressing either Arg1 or iNOS at 4 d after stroke. Data in <i>A</i>–<i>C</i> is presented as average ± SEM. Scale bars represent 32 μm. * <i>P</i> < 0.05; ** <i>P</i> < 0.01; *** <i>P</i> < 0.001.</p
<p>A: Representative cytometry data showing the purity of microglia isolated. Of the isolated cells,...
<p>(<b>A</b> and <b>B</b>) Relative expression of <i>Il1b</i>, <i>Tnfa</i>, and <i>Il10</i> mRNAs in...
<p>Panel A: Total neurological score at 24, 48, 72 h, and 7 days after MCAo. Panel B: Cortical, subc...
<p><b>(A)</b> Expression of innate immune receptors and of <b>(B)</b> signal transduction molecules ...
<p>A. Representative infarctions in the cortex are shown. Animals were euthanized 3 d after stroke. ...
<p><b>A.</b> CD3-positive T-cells invaded the infarct core at 7 d and 28 d following stroke. Increas...
<p><b>Fluorescence labeling of the immune cell markers CD68 and Iba combined with GFAP-immunodetecti...
<p><b>(A)</b> TTC-stained brain section indicating the stroke area (pale color marked by asterisk). ...
Stroke induces a robust inflammatory response. However, it still lacks a systematic view of the vari...
<p>(A) Temporal correlation of activated cells after HI brain injury. Note the 24 h and one week act...
<p><b>A.</b> Post-ischemic Iba1 positive cells (green) displayed the typical activated amoeboid phen...
<p>A. The WT ipsilateral hemispheres display more cells positive for leukocyte esterases than the <i...
Stroke is a multiphasic process, and the initial ischemic phase of neuronal damage is followed by se...
<p>(<b>A</b>) Frequency of TNF-α positive brain microglia in wt and <i>Ns<sup>−/−</sup></i> mice ana...
<p>(A) CD4<sup>+</sup> and CD8<sup>+</sup> T-lymphocytes in unoperated age matched control (left) an...
<p>A: Representative cytometry data showing the purity of microglia isolated. Of the isolated cells,...
<p>(<b>A</b> and <b>B</b>) Relative expression of <i>Il1b</i>, <i>Tnfa</i>, and <i>Il10</i> mRNAs in...
<p>Panel A: Total neurological score at 24, 48, 72 h, and 7 days after MCAo. Panel B: Cortical, subc...
<p><b>(A)</b> Expression of innate immune receptors and of <b>(B)</b> signal transduction molecules ...
<p>A. Representative infarctions in the cortex are shown. Animals were euthanized 3 d after stroke. ...
<p><b>A.</b> CD3-positive T-cells invaded the infarct core at 7 d and 28 d following stroke. Increas...
<p><b>Fluorescence labeling of the immune cell markers CD68 and Iba combined with GFAP-immunodetecti...
<p><b>(A)</b> TTC-stained brain section indicating the stroke area (pale color marked by asterisk). ...
Stroke induces a robust inflammatory response. However, it still lacks a systematic view of the vari...
<p>(A) Temporal correlation of activated cells after HI brain injury. Note the 24 h and one week act...
<p><b>A.</b> Post-ischemic Iba1 positive cells (green) displayed the typical activated amoeboid phen...
<p>A. The WT ipsilateral hemispheres display more cells positive for leukocyte esterases than the <i...
Stroke is a multiphasic process, and the initial ischemic phase of neuronal damage is followed by se...
<p>(<b>A</b>) Frequency of TNF-α positive brain microglia in wt and <i>Ns<sup>−/−</sup></i> mice ana...
<p>(A) CD4<sup>+</sup> and CD8<sup>+</sup> T-lymphocytes in unoperated age matched control (left) an...
<p>A: Representative cytometry data showing the purity of microglia isolated. Of the isolated cells,...
<p>(<b>A</b> and <b>B</b>) Relative expression of <i>Il1b</i>, <i>Tnfa</i>, and <i>Il10</i> mRNAs in...
<p>Panel A: Total neurological score at 24, 48, 72 h, and 7 days after MCAo. Panel B: Cortical, subc...