<p><b>Effect of APAP and SLM on CYP2E1 activity in vivo (A), mRNA expression (B), protein content (C) and CYPE1 activity in vitro (D, E).</b> Results represent mean ± SEM, n = 7. *p < 0.05, **p < 0.01, ***p < 0.001 APAP vs control. <sup>#</sup>p < 0.05, <sup>##</sup>p < 0.01 APAP + SLM vs APAP.</p
Aim: Recently, we have demonstrated that silymarin has a comparable pharmaceutical activity as Phyll...
Acetaminophen (APAP) is commonly used as analgesic and antipyretic drug for relieving mild and moder...
Background and Aim: Laboratory mice are widely used as a research model to provide insights into tox...
Acetaminophen or paracetamol (APAP) overdose is a common cause of liver injury. Silymarin (SLM) is a...
Previous studies have shown that silymarin protects against various types of drug-induced liver inju...
The objective was to investigate if the hepatotoxic sensitivity in nonalcoholic steatohepatitic mice...
Objective: To evaluate the ameliorator property of silymarin or/and Nigella sativa (N. sativa) extra...
This study was aimed to investigate the effect of Silymarin (SLM) on the hypertension state and the ...
<p>(A) TBARS. (B) Oxidized H<sub>2</sub>DCF-DA. (C) Protein carbonyls. Mice were given acetaminophen...
Aim: Recently, we have demonstrated that silymarin has a comparable pharmaceutical activity as Phyll...
Copyright © 2015 Abel Felipe Freitag et al. This is an open access article distributed under the Cre...
902-909Acetaminophen (APAP) is commonly used as analgesic and antipyretic drug for relieving mild an...
Brain is susceptible to oxidative stress and it is associated with age-related brain dysfunction. Pr...
Brain is susceptible to oxidative stress and it is associated with age-related brain dysfunction. Pr...
Brain is susceptible to oxidative stress and it is associated with age-related brain dysfunction. Pr...
Aim: Recently, we have demonstrated that silymarin has a comparable pharmaceutical activity as Phyll...
Acetaminophen (APAP) is commonly used as analgesic and antipyretic drug for relieving mild and moder...
Background and Aim: Laboratory mice are widely used as a research model to provide insights into tox...
Acetaminophen or paracetamol (APAP) overdose is a common cause of liver injury. Silymarin (SLM) is a...
Previous studies have shown that silymarin protects against various types of drug-induced liver inju...
The objective was to investigate if the hepatotoxic sensitivity in nonalcoholic steatohepatitic mice...
Objective: To evaluate the ameliorator property of silymarin or/and Nigella sativa (N. sativa) extra...
This study was aimed to investigate the effect of Silymarin (SLM) on the hypertension state and the ...
<p>(A) TBARS. (B) Oxidized H<sub>2</sub>DCF-DA. (C) Protein carbonyls. Mice were given acetaminophen...
Aim: Recently, we have demonstrated that silymarin has a comparable pharmaceutical activity as Phyll...
Copyright © 2015 Abel Felipe Freitag et al. This is an open access article distributed under the Cre...
902-909Acetaminophen (APAP) is commonly used as analgesic and antipyretic drug for relieving mild an...
Brain is susceptible to oxidative stress and it is associated with age-related brain dysfunction. Pr...
Brain is susceptible to oxidative stress and it is associated with age-related brain dysfunction. Pr...
Brain is susceptible to oxidative stress and it is associated with age-related brain dysfunction. Pr...
Aim: Recently, we have demonstrated that silymarin has a comparable pharmaceutical activity as Phyll...
Acetaminophen (APAP) is commonly used as analgesic and antipyretic drug for relieving mild and moder...
Background and Aim: Laboratory mice are widely used as a research model to provide insights into tox...