5-ASA treatment attenuates plasma lipid levels in HFC-fed mice.

<p>(A) Body weights of HFC and HFC 5-ASA-fed C57BL/6J mice over time, starting at 10–12 weeks of age. (B) Fat or lean mass to body weight ratio were assessed after 12 weeks of HFC or HFC 5-ASA. (C) Food intake of mice fed HFC and HFC 5-ASA at the first week and week 11. (D-E) Fasting glucose and fasting insulin of mice after 11 weeks of HFC or HFC 5-ASA. (F-H) Plasma triglycerides, free cholesterol and total cholesterol levels of 12-weeks HFC or HFC 5-ASA-fed mice. Data are presented as means ± SEM, n = 9–10 mice, ^aP < 0.05 vs. HFC, ^bP < 0.01 vs. HFC.