Additional file 1: Figure S1. of Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin

Characteristics of vaginal microbiota groups (VMGs) defined using Ward clustering. Figure S2. Bacterial taxonomic groups discriminate between normal-term delivery and samples taken following membrane rupture. Figure S3. Bacterial taxonomic groups associated with early onset neonatal sepsis (EONS) following PPROM, for neonates delivered at or before 28 weeks gestation (n = 27). Table S1. Bacterial diversity, richness and relative abundance of Lactobacillus spp. for VMGs 1–8. Table S2. Linear regression analysis comparing proportion of Lactobacillus spp. dominance across all patient groups corrected for potential confounders. Table S3. Linear regression analysis comparing proportion of Lactobacillus spp. dominance in paired samples before and after 48 hours erythromycin treatment. Table S4. Maternal and neonatal factors in the presence and absence of chorioamnionitis +/- funisitis. Table S5. Linear regression analysis comparing proportion of Lactobacillus spp. dominance in cases with and without chorioamnionitis +/- funisitis. Table S6. Maternal and neonatal factors associated with EONS. (DOCX 1632 kb