The effect of CORT and EGCG on ERK1/2 and AKT mRNA in primary hippocampal neurons.

<p>Primary hippocampal neuron cultures were pre-treated with EGCG for 2 h at indicated concentrations before stimulation with CORT for 24 h. The total RNA was isolated to measure the expression of ERK1/2 and AKT mRNA by RT-PCR, and expressed as mean ± SD of GAPDH mRNA levels. A) The expression of ERK1/2 mRNA; B) The expression of AKT mRNA. ^a <i>P</i><0.05 <i>vs</i> normal control group: ^b <i>P</i><0.05 <i>vs</i> CORT treatment group.