<p>Free energy landscape of HER-2 as a function of first two principal components PC1 and PC2 (A) wild, (B) K753E.</p
A) SKBR3 breast cancer cells were cultured in lapatinib till they gained resistance and started acti...
HER2 overexpression has been implicated in breast cancer. Lapatinib is a dual EGFR/HER2 tyrosine kin...
From the Washington University Senior Honors Thesis Abstracts (WUSHTA), 2017. Published by the Offic...
<p>Free energy landscape of HER-2 as a function of first two principal components PC1 and PC2 (A) L7...
<p>(A) MM/PBSA free energy calculation of HER-2 L755S-Lapatinib complex, (B) Free energy decompositi...
<p>(A) Backbone RMSD’s as a function of time for wild and mutant HER-2 in complex with lapatinib, (B...
HER-2 belongs to the human epidermal growth factor receptor (HER) family. Via different signal trans...
HER2-targeted therapies have greatly improved the outcome for patients with HER2-positive breast can...
The pressure exerted by drugs targeted to a protein in any therapy inevitably leads to the emergence...
The pressure exerted by drugs targeted to a protein in any therapy inevitably leads to the emergence...
The pressure exerted by drugs targeted to a protein in any therapy inevitably leads to the emergence...
The pressure exerted by drugs targeted to a protein in any therapy inevitably leads to the emergence...
Purpose: Resistance to anti-HER2 therapies in HER2+ breast cancer can occur through activation of al...
[[abstract]]HER2 is a major proliferative driver in lung cancer and the role of HER2-targeting drugs...
Background: HER2 targeted therapies including trastuzumab and more recently lapatinib have significa...
A) SKBR3 breast cancer cells were cultured in lapatinib till they gained resistance and started acti...
HER2 overexpression has been implicated in breast cancer. Lapatinib is a dual EGFR/HER2 tyrosine kin...
From the Washington University Senior Honors Thesis Abstracts (WUSHTA), 2017. Published by the Offic...
<p>Free energy landscape of HER-2 as a function of first two principal components PC1 and PC2 (A) L7...
<p>(A) MM/PBSA free energy calculation of HER-2 L755S-Lapatinib complex, (B) Free energy decompositi...
<p>(A) Backbone RMSD’s as a function of time for wild and mutant HER-2 in complex with lapatinib, (B...
HER-2 belongs to the human epidermal growth factor receptor (HER) family. Via different signal trans...
HER2-targeted therapies have greatly improved the outcome for patients with HER2-positive breast can...
The pressure exerted by drugs targeted to a protein in any therapy inevitably leads to the emergence...
The pressure exerted by drugs targeted to a protein in any therapy inevitably leads to the emergence...
The pressure exerted by drugs targeted to a protein in any therapy inevitably leads to the emergence...
The pressure exerted by drugs targeted to a protein in any therapy inevitably leads to the emergence...
Purpose: Resistance to anti-HER2 therapies in HER2+ breast cancer can occur through activation of al...
[[abstract]]HER2 is a major proliferative driver in lung cancer and the role of HER2-targeting drugs...
Background: HER2 targeted therapies including trastuzumab and more recently lapatinib have significa...
A) SKBR3 breast cancer cells were cultured in lapatinib till they gained resistance and started acti...
HER2 overexpression has been implicated in breast cancer. Lapatinib is a dual EGFR/HER2 tyrosine kin...
From the Washington University Senior Honors Thesis Abstracts (WUSHTA), 2017. Published by the Offic...
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