Additional file 10: Table S3. of Large-scale genomic analysis shows association between homoplastic genetic variation in Mycobacterium tuberculosis genes and meningeal or pulmonary tuberculosis

Protein prediction for genomic sites associated with the TB disease phenotype. NA: No homologs of Rv0192 were found therefore protein prediction was not possible. # I-mutant predicts free energy changes of protein stability upon a point mutation under different conditions. & PolyPhen predicts the possible impact of an amino acid substitution on the structure and function of a human protein using straightforward physical and comparative considerations. ^ TargetP predicts the subcellular location of proteins based on the predicted presence of any N-terminal signal peptides. * TMHMM predicts transmembrane helices in proteins. (DOCX 57Â kb