These data would support a model where barrier dysfunction possibly promotes greater allergen penetration and delivery to drive allergen-specific CD4+ T cells. This could further contribute to respiratory and cutaneous inflammatory disease
Background: Mutations in the filaggrin gene (FLG) have been shown to play a significant role in icht...
Human skin constitutes a highly organized barrier against environmental agents. Its unrestricted fun...
Our understanding of the pathogenesis of atopic dermatitis has been dramatically enhanced following ...
BACKGROUND: Filaggrin null mutations associate with atopic eczema and also with asthma when present ...
Recent genetic findings demonstrate an important role for the epidermal protein filaggrin in the aet...
The recent identification of loss-of-function mutations in the structural protein filaggrin as a wid...
BACKGROUND: Childhood eczema often precedes the development of asthma and allergic rhinitis in the s...
The recent identification of loss-of-function mutations in the structural protein filaggrin as a wid...
ABSTRACTFilaggrin is a key protein that facilitates terminal differentiation of the epidermis and fo...
The discovery that null mutations in the filaggrin gene (FLG) are associated with atopic eczema repr...
Background: Mutations in the filaggrin gene (FLG) have been shown to play a significant role in icht...
Human skin constitutes a highly organized barrier against environmental agents. Its unrestricted fun...
Our understanding of the pathogenesis of atopic dermatitis has been dramatically enhanced following ...
BACKGROUND: Filaggrin null mutations associate with atopic eczema and also with asthma when present ...
Recent genetic findings demonstrate an important role for the epidermal protein filaggrin in the aet...
The recent identification of loss-of-function mutations in the structural protein filaggrin as a wid...
BACKGROUND: Childhood eczema often precedes the development of asthma and allergic rhinitis in the s...
The recent identification of loss-of-function mutations in the structural protein filaggrin as a wid...
ABSTRACTFilaggrin is a key protein that facilitates terminal differentiation of the epidermis and fo...
The discovery that null mutations in the filaggrin gene (FLG) are associated with atopic eczema repr...
Background: Mutations in the filaggrin gene (FLG) have been shown to play a significant role in icht...
Human skin constitutes a highly organized barrier against environmental agents. Its unrestricted fun...
Our understanding of the pathogenesis of atopic dermatitis has been dramatically enhanced following ...
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