This article searches the contours of anxiety, asking whether anxiety can serve as a springboard to creative engagement in dialogue. Specifically, the article explores the university classroom as a possible site where anxiety might be transformed into the spark of creation. Three opportune moments are examined—disruption, silence, and creation— for the possibilities they present for creating new spaces of energy and new engagement with the call of alterity that erupts in human encounter. The encounter with an “Other” who calls to us from across a chasm of difference—a call that demands a response—is the opening to the possibility of creative engagement that can lead to new levels of transcendence in the classroom and beyond