Increased colon cancer risk after severe Salmonella infection.
- Mughini-Gras, Lapo
- Schaapveld, Michael
- Kramers, Jolanda
- Mooij, Sofie
- Neefjes-Borst, E Andra
- Pelt, Wilfrid van
- Neefjes, Jacques
Publication date
January 2018
DOI Publisher
Public Library of Science (PLoS) ISSN
1932-6203 Journal
PLoS ONE Citation count (estimate)
1Abstract
Colon cancer constitutes one of the most frequent malignancies. Previous studies showed that Salmonella manipulates host cell signaling pathways and that Salmonella Typhimurium infection facilitates colon cancer development in genetically predisposed mice. This epidemiological study examined whether severe Salmonella infection, usually acquired from contaminated food, is associated with increased colon cancer risk in humans
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