A new approach for optimization of electrospun nanofiber formation process

Precise control of fiber diameter during electrospinning is very crucial for many applications. A systematicand quantitative study on the effects of processing variables enables us to control the properties of electrospun nanofibers.In this contribution, response surface methodology (RSM) was employed to quantitatively investigate the simultaneouseffects of four of the most important parameters, namely solution concentration (C), spinning distance (d),applied voltage (V) and volume flow rate (Q), on mean fiber diameter (MFD) as well as standard deviation of fiberdiameter (StdFD) in electrospinning of polyvinyl alcohol (PVA) nanofibers